I haven't played that many ST games. EF1 was excellent, as was Birth of the Federation... SF Command 1 is the only one of that series I played, and it was good too. I liked Star Trek Armada, and the idea behind the ability to port in ships from Starship Creator 2 (another awesome game) was cool, even if it didn't necessarily work that well. The Final Unity was fun too. Star Trek Online is alright.

What about board games? Anyone else play the Interactive VCR Board Game? "Yes Captain Kovak!" I also have "The Game of the Galaxies," which was fun when I was a kid...

For me personally, I'd have to say that Birth of the Federation was my favorite.